Marijuana Compounds: A Nonconventional Approach to Parkinson’s Disease Therapy

10 Oct 2016Mariana Babayeva, Haregewein Assefa, Paramita Basu, Sanjeda Chumki, and Zvi Loewy

Marijuana has been shown to improve nonmotor symptoms of PD such as depression, pain, sleep, and anxiety. Moreover, components of cannabis have been demonstrated to have neuroprotective effect due to their anti-inflammatory, antioxidative, and antiexcitotoxic properties

Meta Analysis
11 effects

Reported Outcomes

CausesOutcomeCertainty

Marijuana Herb risk & protective factor

Oxidative stress Lymphatic outcome
Minor decreased risk of Oxidative stress
Lymphatic system

Low evidence
-1.0%

Marijuana Herb risk & protective factor

Fatigue Musculoskeletal outcome
Minor decreased risk of Fatigue
Musculoskeletal system

Low evidence
-1.0%

Marijuana Herb risk & protective factor

Memory Brain outcome
Minor decreased risk of Memory
Brain system

Low evidence
-1.0%

Marijuana Herb risk & protective factor

Stress Brain outcome
Minor decreased risk of Stress
Brain system

High evidence
-1.0%

Marijuana Herb risk & protective factor

Pain Sensory outcome
Minor decreased risk of Pain
Sensory system

High evidence
-3.0%

Marijuana Herb risk & protective factor

Sleep Musculoskeletal outcome
Minor increase risk of Sleep
Musculoskeletal system

High evidence
3.0%

Marijuana Herb risk & protective factor

Subjective well-being Brain outcome
Minor increase risk of Subjective well-being
Brain system

High evidence
3.0%

Marijuana Herb risk & protective factor

Neuropathy Sensory outcome
Minor decreased risk of Neuropathy
Sensory system

Low evidence
-1.0%

Marijuana Herb risk & protective factor

Parkinson's Disease Brain outcome
Minor decreased risk of Parkinson's Disease
Brain system

High evidence
-1.0%

Marijuana Herb risk & protective factor

Inflammation Lymphatic outcome
Minor decreased risk of Inflammation
Lymphatic system

High evidence
-1.0%

Marijuana Herb risk & protective factor

Dementia Brain outcome
Minor decreased risk of Dementia
Brain system

Low evidence
-1.0%