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Targeting metastasis-initiating cells thro...

Targeting metastasis-initiating cells through the fatty acid receptor CD36

07 Dec 2016Gloria Pascual, Alexandra Avgustinova, Stefania Mejetta, Mercè Martín, Andrés Castellanos, Camille Stephan-Otto Attolini, Antoni Berenguer, Neus Prats, Agustí Toll, Juan Antonio Hueto, Coro Bescós, Luciano Di Croce & Salvador Aznar Benitah

The team identified overexpression of a protein called CD36. When this protein was added to non-metastatic cancer cells, they started to metastasize, confirming the role of CD36 in the spread of cancer.

Cohort Study
5 effects

Reported Outcomes

DeterminantsOutcomeDetails

Saturated Fat Nutrition risk & protective factor
Minor Risk Factor Saturated Fat
Nutrition

Ovary cancer Reproductive outcome
Minor increase risk of Ovary cancer
Reproductive system

Low evidence
50.0%

Saturated Fat Nutrition risk & protective factor
Minor Risk Factor Saturated Fat
Nutrition

Lung cancer Respiratory outcome
Minor increase risk of Lung cancer
Respiratory system

Low evidence
1.0%

Saturated Fat Nutrition risk & protective factor
Minor Risk Factor Saturated Fat
Nutrition

Bladder cancer Urinary outcome
Minor increase risk of Bladder cancer
Urinary system

Low evidence
1.0%

Saturated Fat Nutrition risk & protective factor
Minor Risk Factor Saturated Fat
Nutrition

Skin cancer Intergumentary outcome
Minor increase risk of Skin cancer
Intergumentary system

Low evidence
1.0%

Saturated Fat Nutrition risk & protective factor
Minor Risk Factor Saturated Fat
Nutrition

Breast Cancer Reproductive outcome
Minor increase risk of Breast Cancer
Reproductive system

Low evidence
1.0%

Risk Factors

NutritionBeveragesHerbsSelf-careContaminantsManufactured

Outcomes

Physical PerformanceBrain & Mental HealthCardiovascularDigestiveEndocrine & HormonesIntergumentary
Lymphatic & Immune systemMaternityRespiratoryReproductiveSensoryUrinary & Kidney

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