Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models

Compared with women who lived in areas exposed to low PM2.5 levels, those who resided in areas with high PM2.5 levels - defined as levels that that exceeded the EPA's permissible limit in 2012 (35 micrograms per cubic meter of air) - were found to be at an 81 percent greater risk of global cognitive decline and have a 92 percent increased risk of developing Alzheimer's disease and other dementias.