Treatment of anxiety, tension and restlessness states with Kava special extract WS 1490 in general practice: a randomized placebo-controlled double-blind multicenter trial.

10 Nov 2003Gastpar M, Klimm HD.

150mg of Kava WS 1490 extract daily in persons suffering from neurotic anxiety noted significant reductions in anxiety as assessed by the Anxiety Status Inventory (ASI) after 4 weeks of treatment.

No effect on liver enzymes (Alkaline Phosphatase, y-GT, GOT, GPT) in this trial

Randomized Controlled Trial
6 effects
2-4 weeks
141 subjects

Reported Outcomes

CausesOutcomeCertainty

Kava Herb risk & protective factor
Kava
Herb

Fatigue Musculoskeletal outcome
Minor decreased risk of Fatigue
Musculoskeletal system

Moderate evidence
-1.0%

Kava Herb risk & protective factor
Kava
Herb

Cognitive deficit Brain outcome
Minor decreased risk of Cognitive deficit
Brain system

Moderate evidence
-1.0%

Kava Herb risk & protective factor
Kava
Herb

Depression Brain outcome
Minor decreased risk of Depression
Brain system

Moderate evidence
-1.0%

Kava Herb risk & protective factor
Kava
Herb

Subjective well-being Brain outcome
Minor increase risk of Subjective well-being
Brain system

Moderate evidence
3.0%

Kava Herb risk & protective factor
Kava
Herb

Blood Pressure - Hypertension Cardiovascular outcome
Minor decreased risk of Blood Pressure - Hype...
Cardiovascular system

Moderate evidence
-1.0%

Kava Herb risk & protective factor
Kava
Herb

Stress Brain outcome
Minor decreased risk of Stress
Brain system

Moderate evidence
-3.0%