Perinatal and Neonatal Risk Factors for Autism: A Comprehensive Meta-analysis | OutcomeReference

15 Aug 2011Hannah Gardener, ScD, Donna Spiegelman, ScD, and Stephen L. Buka, ScD

a broad class of conditions reflecting general compromises to perinatal and neonatal health may increase the risk of autism

Meta Analysis

9 effects

Determinants	Outcome	Details
Anemia Lymphatic system	Strong increased risk of Autism Maternity system	High evidence 687.0%
Congenital Anomaly Maternity system	Increased risk of Autism Maternity system	High evidence 80.0%
Low birth weight Maternity system	Increased risk of Autism Maternity system	High evidence 63.0%
Apgar score Maternity system	Decreased risk of Autism Maternity system	High evidence -67.0%
Caesarean delivery Maternity system	Minor increase risk of Autism Maternity system	Low evidence 26.0%
Concussion (Traumatic... Brain system	Strong increased risk of Autism Maternity system	Moderate evidence 390.0%
Injury Musculoskeletal system	Strong increased risk of Autism Maternity system	Moderate evidence 390.0%
Hyperbilirubinemia Urinary system	Increased risk of Autism Maternity system	High evidence 87.0%
Maternal bleeding Maternity system	Strong increased risk of Autism Maternity system	High evidence 139.0%