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Outcomes
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Age at Menarche and Risks of All-Cause and...

Age at Menarche and Risks of All-Cause and Cardiovascular Death: A Systematic Review and Meta-Analysis

11 Jun 2014Dimitrios Charalampopoulos Andrew McLoughlin Cathy E. Elks Ken K. Ong

Early menarche was consistently associated with higher risk of death from all causes.

Meta Analysis
4 effects

Reported Outcomes

DeterminantsOutcomeDetails

Early Menarche Reproductive outcome
Early Menarche
Reproductive system

Mortality Musculoskeletal outcome
Minor increase risk of Mortality
Musculoskeletal system

High evidence
23.0%

Early Menarche Reproductive outcome
Early Menarche
Reproductive system

Stroke Brain outcome
Minor increase risk of Stroke
Brain system

Moderate evidence
5.0%

Early Menarche Reproductive outcome
Early Menarche
Reproductive system

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Minor increase risk of Coronary Heart Diseas...
Cardiovascular system

High evidence
22.0%

Early Menarche Reproductive outcome
Early Menarche
Reproductive system

Cardiovascular Disease Cardiovascular outcome
Minor increase risk of Cardiovascular Disease
Cardiovascular system

Moderate evidence
5.0%

Risk Factors

NutritionBeveragesHerbsSelf-careContaminantsManufactured

Outcomes

Physical PerformanceBrain & Mental HealthCardiovascularDigestiveEndocrine & HormonesIntergumentary
Lymphatic & Immune systemMaternityRespiratoryReproductiveSensoryUrinary & Kidney

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