Coffee, tea, caffeine and risk of depression: A systematic review and dose–response meta-analysis of observational studies

Giuseppe Grosso, Agnieszka Micek, Sabrina Castellano, Andzrej Pajak, Fabio Galvano

This study suggests a protective effect of coffee and, partially, of tea and caffeine on risk of depression.

Systematic review
2 effects
1998-2015
346913 subjects

Reported Outcomes

DeterminantsOutcomeDetails

Green Tea Beverage risk & protective factor
Minor Protective Factor Green Tea
Beverage

Depression Brain outcome
Minor decreased risk of Depression
Brain system

Moderate evidence
-30.0%

Coffee (Caffeine) Beverage risk & protective factor
Minor Protective Factor Coffee (Caffeine)
Beverage

Depression Brain outcome
Minor decreased risk of Depression
Brain system

High evidence
-24.0%