Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease

05 Jan 2017Sanna Torvinen-Kiiskinen, Anna-Maija Tolppanen, Marjaana Koponen, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen, Heidi Taipale

Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease

Cross-section study
3 effects
151473 subjects

Reported Outcomes

DeterminantsOutcomeDetails

Antidepressants Manufactured risk & protective factor
Minor Risk Factor Antidepressants
Manufactured

Fracture Musculoskeletal outcome
Minor increase risk of Fracture
Musculoskeletal system

Low evidence
128.0%

Antidepressants Manufactured risk & protective factor
Risk Factor Antidepressants
Manufactured

Fracture Musculoskeletal outcome
Increased risk of Fracture
Musculoskeletal system

Moderate evidence
201.0%

Antidepressants Manufactured risk & protective factor
Strong Risk Factor Antidepressants
Manufactured

Hip fracture Musculoskeletal outcome
Strong increased risk of Hip fracture
Musculoskeletal system

High evidence
128.0%