Association of Environmental Toxins With Amyotrophic Lateral Sclerosis

22 Aug 2016Feng-Chiao Su, PhD; Stephen A. Goutman, MD; Sergey Chernyak, PhD

In this study, persistent environmental pollutants measured in blood were significantly associated with ALS and may represent modifiable ALS disease risk factors.

Case-control study
4 effects
284 subjects

Reported Outcomes

CausesOutcomeCertainty

Pesticides Exposure Contaminant risk & protective factor

Amyotrophic lateral sclerosis (ALS) Nervous outcome
Strong increased risk of Amyotrophic lateral s...
Nervous system

Moderate evidence
121.0%

Polychlorinated Biphenyl (PCB)  Contaminant risk & protective factor

Amyotrophic lateral sclerosis (ALS) Nervous outcome
Strong increased risk of Amyotrophic lateral s...
Nervous system

Moderate evidence
111.0%

Bisphenol A (BPA) Contaminant risk & protective factor

Amyotrophic lateral sclerosis (ALS) Nervous outcome
Strong increased risk of Amyotrophic lateral s...
Nervous system

Moderate evidence
169.0%

Bisphenol A (BPA) Contaminant risk & protective factor

Amyotrophic lateral sclerosis (ALS) Nervous outcome
Strong increased risk of Amyotrophic lateral s...
Nervous system

Moderate evidence
169.0%