Short inter-set rest blunts resistance exercise-induced increases in myofibrillar protein synthesis and intracellular signalling in young males

02 Jun 2016James McKendry, Alberto Pérez-López, Michael McLeod, Dan Luo, Jessica R. Dent, Benoit Smeuninx, Jinglei Yu, Angela E. Taylor, Andrew Philp, Leigh Breen

Resistance exercise with short (1 min) inter-set rest duration attenuated myofibrillar protein synthesis during the early postexercise recovery period compared with longer (5 min) rest duration, potentially through compromised activation of intracellular signalling.

Cohort Study
1 effect
24 hours
16 subjects

Reported Outcomes


Exercise Recovery Musculoskeletal outcome
Exercise Recovery
Musculoskeletal system

Strength Musculoskeletal outcome
Increased risk of Strength
Musculoskeletal system

Moderate evidence