Carbamate Insecticides Target Human Melatonin Receptors

27 Dec 2016Marina Popovska-Gorevski, Margarita L. Dubocovich, and Rajendram V. Rajnarayanan

data points to a potentially new mechanism through which carbamate insecticides carbaryl and carbofuran could impact human health by altering the homeostatic balance of key regulatory processes by directly binding to melatonin receptors.

Medical Discussion
2 effects

Reported Outcomes

CausesOutcomeCertainty

Pesticides Exposure Contaminant risk & protective factor

Poor sleep Musculoskeletal outcome
Minor increase risk of Poor sleep
Musculoskeletal system

Low evidence
12.0%

Pesticides Exposure Contaminant risk & protective factor

Type 2 Diabetes Lymphatic outcome
Minor increase risk of Type 2 Diabetes
Lymphatic system

Low evidence
6.0%