Intake of individual saturated fatty acids and risk of coronary heart disease in US men and women: two prospective longitudinal cohort studies

21 Oct 2016geng Zong, postdoctoral fellow, Yanping Li, research scientist, Anne J Wanders, research scientist, Marjan Alssema, lead scientist, Peter L Zock, science leader, Walter C Willett, professor, Frank B Hu, professor, Qi Sun, assistant professor

Higher dietary intakes of major SFAs are associated with an increased risk of coronary heart disease. Owing to similar associations and high correlations among individual SFAs, dietary recommendations for the prevention of coronary heart disease should continue to focus on replacing total saturated fat with more healthy sources of energy.

Cohort Study
6 effects
1984-2012
115782 subjects

Reported Outcomes

CausesOutcomeCertainty

Saturated Fat Nutrition risk & protective factor
Saturated Fat
Nutrition

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Minor increase risk of Coronary Heart Diseas...
Cardiovascular system

High evidence
18.0%

Vegetables Nutrition risk & protective factor
Vegetables
Nutrition

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Minor decreased risk of Coronary Heart Diseas...
Cardiovascular system

High evidence
-7.0%

Unsaturated fat Nutrition risk & protective factor

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Minor decreased risk of Coronary Heart Diseas...
Cardiovascular system

High evidence
-11.0%

Whole grains Nutrition risk & protective factor
Whole grains
Nutrition

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Minor decreased risk of Coronary Heart Diseas...
Cardiovascular system

High evidence
-6.0%

Unsaturated fat Nutrition risk & protective factor

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

High evidence
-12.0%

Whole grains Nutrition risk & protective factor
Whole grains
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

High evidence
-10.0%