Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study

12 Jan 2017 Fenesi, Barbara | Fang, Hanna | Kovacevic, Ana | Oremus, Mark | Raina, Parminder | Heisz, Jennifer J

This research shows that exercise can mitigate the risk of dementia for people without the variant of the apolipoprotein genotype

Cohort Study
2 effects
5 years
1646 subjects

Reported Outcomes

CausesOutcomeCertainty

Moderate Exercise Selfcare risk & protective factor

Dementia Brain outcome
Decreased risk of Dementia
Brain system

Moderate evidence
-98.0%

Sedentary Lifestyle Selfcare risk & protective factor

Dementia Brain outcome
Increased risk of Dementia
Brain system

Moderate evidence
98.0%