A Breathing-Based Meditation Intervention for Patients With Major Depressive Disorder Following Inadequate Response to Antidepressants: A Randomized Pilot Study

22 Nov 2016Anup Sharma, MD, PhD; Marna S. Barrett, PhD; Andrew J. Cucchiara, PhD; Nalaka S. Gooneratne, MD; and Michael E. Thase, MD

Results of this randomized, waitlist-controlled pilot study suggest the feasibility and promise of an adjunctive SKY-based intervention for patients with MDD who have not responded to antidepressants.

Randomized Controlled Trial
2 effects
8 weeks
25 subjects

Reported Outcomes

DeterminantsOutcomeDetails

Yoga Selfcare risk & protective factor
Minor Protective Factor Yoga
Selfcare

Depression Brain outcome
Minor decreased risk of Depression
Brain system

Low evidence
-42.0%

Yoga Selfcare risk & protective factor
Minor Protective Factor Yoga
Selfcare

Anxiety Brain outcome
Minor decreased risk of Anxiety
Brain system

Low evidence
-23.5%