Psychotropic medications and the risk of sudden cardiac death during an acute coronary event

14 Sep 2011Jussi Honkola, Eeva Hookana, Sanna Malinen, Kari S. Kaikkonen, M. Juhani Junttila, Matti Isohanni, Marja-Leena Kortelainen, Heikki V. Huikuri

The use of psychotropic drugs, especially combined use of antipsychotic and antidepressant drugs, is strongly associated with an increased risk of SCD at the time of an acute coronary event.

Cohort Study
2 effects
1814 subjects

Reported Outcomes

CausesOutcomeCertainty

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Mortality Musculoskeletal outcome
Strong increased risk of Mortality
Musculoskeletal system

High evidence
340.0%

Antipsychotics Manufactured risk & protective factor
Antipsychotics
Manufactured

Mortality Musculoskeletal outcome
Strong increased risk of Mortality
Musculoskeletal system

High evidence
340.0%