Aerobic training decreases bronchial hyperresponsiveness and systemic inflammation in patients with moderate or severe asthma: a randomised controlled trial

10 Jun 2015Andrezza França-Pinto, Felipe A R Mendes, Regina Maria de Carvalho-Pinto, Rosana Câmara Agondi, Alberto Cukier, Rafael Stelmach, Beatriz M Saraiva-Romanholo, Jorge Kalil, Milton A Martins, Pedro Giavina-Bianchi, Celso R F Carvalho

Aerobic training reduced bronchial hyperresponsiveness (BHR) and serum proinflammatory cytokines and improved quality of life and asthma exacerbation in patients with moderate or severe asthma. These results suggest that adding exercise as an adjunct therapy to pharmacological treatment could improve the main features of asthma.

Cohort Study
2 effects
3 months
58 subjects

Reported Outcomes

CausesOutcomeCertainty

Moderate Exercise Selfcare risk & protective factor

Asthma Attack Respiratory outcome
Strong decrease risk of Asthma Attack
Respiratory system

Moderate evidence
-100.0%

Moderate Exercise Selfcare risk & protective factor

Oxidative stress Lymphatic outcome
Minor decreased risk of Oxidative stress
Lymphatic system

Low evidence
-15.0%