Caffeine regulates frontocorticostriatal dopamine transporter density and improves attention and cognitive deficits in an animal model of attention deficit hyperactivity disorder

15 Apr 2013Pablo Pandolfo, Nuno J. Machado, Attila Köfalvi, Reinaldo N. Takahashi, Rodrigo A. Cunha

These findings underscore the potential for caffeine treatment to normalize frontocortical dopaminergic function and to abrogate attention and cognitive changes characteristic of ADHD.

Animal Research
3 effects

Reported Outcomes

CausesOutcomeCertainty

Coffee (Caffeine) Beverage risk & protective factor

Attention deficit hyperactivity disorder (ADHD) Maternity outcome
Decreased risk of Attention deficit hyp...
Maternity system

Low evidence
-66.0%

Coffee (Caffeine) Beverage risk & protective factor

Learning Ability Brain outcome
Minor increase risk of Learning Ability
Brain system

Low evidence
9.0%

Coffee (Caffeine) Beverage risk & protective factor

Cognitive Activity Brain outcome
Minor increase risk of Cognitive Activity
Brain system

Low evidence
9.0%