Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies

08 Dec 2016Xuexian Fang, Kai Wang, Dan Han, Xuyan He, Jiayu Wei, Lu Zhao, Mustapha Umar Imam, Zhiguang Ping, Yusheng Li, Yuming Xu, Junxia Min and Fudi Wang

Increasing dietary magnesium intake is associated with a reduced risk of stroke, heart failure, diabetes, and all-cause mortality, but total cardiovascular disease. These findings support the notion that increasing dietary magnesium might provide health benefits.

Meta Analysis
32 effects
14 years
1000000 subjects

Reported Outcomes

CausesOutcomeCertainty

Cacao Nutrition risk & protective factor
Cacao
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Cacao Nutrition risk & protective factor
Cacao
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Cacao Nutrition risk & protective factor
Cacao
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Cacao Nutrition risk & protective factor
Cacao
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Bananas Nutrition risk & protective factor
Bananas
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Bananas Nutrition risk & protective factor
Bananas
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Soy Nutrition risk & protective factor
Soy
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Soy Nutrition risk & protective factor
Soy
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Soy Nutrition risk & protective factor
Soy
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Soy Nutrition risk & protective factor
Soy
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Nuts & Peanuts Nutrition risk & protective factor

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Nuts & Peanuts Nutrition risk & protective factor

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Nuts & Peanuts Nutrition risk & protective factor

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Nuts & Peanuts Nutrition risk & protective factor

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Yoghurt Nutrition risk & protective factor
Yoghurt
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Low evidence
-10.0%

Yoghurt Nutrition risk & protective factor
Yoghurt
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Low evidence
-19.0%

Bananas Nutrition risk & protective factor
Bananas
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Bananas Nutrition risk & protective factor
Bananas
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Fish & SeaFood rich in Omega-3 Nutrition risk & protective factor

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Fish & SeaFood rich in Omega-3 Nutrition risk & protective factor

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Fish & SeaFood rich in Omega-3 Nutrition risk & protective factor

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Fish & SeaFood rich in Omega-3 Nutrition risk & protective factor

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Yoghurt Nutrition risk & protective factor
Yoghurt
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Low evidence
-22.0%

Yoghurt Nutrition risk & protective factor
Yoghurt
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Low evidence
-7.0%

Broccoli Nutrition risk & protective factor
Broccoli
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Broccoli Nutrition risk & protective factor
Broccoli
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%

Broccoli Nutrition risk & protective factor
Broccoli
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Broccoli Nutrition risk & protective factor
Broccoli
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Spinach Nutrition risk & protective factor
Spinach
Nutrition

Mortality Musculoskeletal outcome
Minor decreased risk of Mortality
Musculoskeletal system

Moderate evidence
-10.0%

Spinach Nutrition risk & protective factor
Spinach
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Moderate evidence
-19.0%

Spinach Nutrition risk & protective factor
Spinach
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Moderate evidence
-7.0%

Spinach Nutrition risk & protective factor
Spinach
Nutrition

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Minor decreased risk of Heart Attack (Myocard...
Cardiovascular system

Moderate evidence
-22.0%