Acute and chronic effect of aspirin on selected endurance variables

Subjects reported a significantly higher local rating of perceived exertion (p ≤ 0.001) at maximal effort following both the chronic and acute treatments with ingestion of aspirin. Additionally, a significantly higher maximal minute ventilation (p S 0.05) was observed for chronic treatment compared with the placebo. The results of this study suggest that respiratory gas exchange and metabolic and psychological variables are negatively affected by ingestion of aspirin prior to exercise.