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Risk Factors
NutritionNutritionDrinks & beveragesBeveragesHerbHerbsSelfcareSelfcareContaminantContaminantsManufactured substancesManufactured
Outcomes
PerformanceBrainCardiovascularDigestiveEndocrineIntergumentaryLymphaticMaternityRespiratoryReproductiveSensoryUrinary
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Chronic Sleep Disruption Alters Gut Microb...

Chronic Sleep Disruption Alters Gut Microbiota, Induces Systemic and Adipose Tissue Inflammation and Insulin Resistance in Mice

14 Oct 2016Valeriy A. Poroyko, Alba Carreras, Abdelnaby Khalyfa, Ahamed A. Khalyfa, Vanessa Leone, Eduard Peris, Isaac Almendros, Alex Gileles-Hillel, Zhuanhong Qiao, Nathaniel Hubert, Ramon Farré, Eugene B. Chang & David Gozal

Chronic sleep fragmentation may increase inflammation, insulin and adiposity in mice.

Animal Research
6 effects
6 weeks

Reported Outcomes

DeterminantsOutcomeDetails

Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal system

Insulin Resistance Lymphatic outcome
Minor increase risk of Insulin Resistance
Lymphatic system

Low evidence
125.0%

Sleep Musculoskeletal outcome
Sleep
Musculoskeletal system

Insulin Resistance Lymphatic outcome
Minor decreased risk of Insulin Resistance
Lymphatic system

Low evidence
-125.0%

Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal system

Fat Oxidation Musculoskeletal outcome
Minor decreased risk of Fat Oxidation
Musculoskeletal system

Low evidence
-25.0%

Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal system

Appetite Digestive outcome
Minor increase risk of Appetite
Digestive system

Low evidence
70.0%

Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal system

Metabolic Syndrome Lymphatic outcome
Minor increase risk of Metabolic Syndrome
Lymphatic system

Low evidence
25.0%

Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal system

Inflammation Lymphatic outcome
Minor increase risk of Inflammation
Lymphatic system

Low evidence
75.0%

Risk Factors

NutritionBeveragesHerbsSelf-careContaminantsManufactured

Outcomes

Physical PerformanceBrain & Mental HealthCardiovascularDigestiveEndocrine & HormonesIntergumentary
Lymphatic & Immune systemMaternityRespiratoryReproductiveSensoryUrinary & Kidney

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