Effects of phlebotomy-induced reduction of body iron stores on metabolic syndrome: results from a randomized clinical trial

30 May 2012Khosrow S Houschyar, Rainer Lüdtke, Gustav J Dobos, Ulrich Kalus, Martina Broecker-Preuss, Thomas Rampp, Benno Brinkhaus, and Andreas Michals

In patients with METS, phlebotomy, with consecutive reduction of body iron stores, lowered BP and resulted in improvements in markers of cardiovascular risk and glycemic control. Blood donation may have beneficial effects for blood donors with METS.

Randomized Controlled Trial
4 effects
6 weeks
64 subjects

Reported Outcomes

CausesOutcomeCertainty

Blood Donation Selfcare risk & protective factor

Insulin Resistance Lymphatic outcome
Minor decreased risk of Insulin Resistance
Lymphatic system

Low evidence
-1.9%

Blood Donation Selfcare risk & protective factor

LDL Lymphatic outcome
Minor decreased risk of LDL
Lymphatic system

Low evidence
-6.2%

Blood Donation Selfcare risk & protective factor

Heart Rate Cardiovascular outcome
Minor decreased risk of Heart Rate
Cardiovascular system

Low evidence
-15.0%

Blood Donation Selfcare risk & protective factor

Blood Pressure - Hypertension Cardiovascular outcome
Minor decreased risk of Blood Pressure - Hype...
Cardiovascular system

Moderate evidence
-13.7%