Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis

20 Jun 2005Hsu-Ko Kuo, MPH, MD, Dr Chung-Jen Yen, MD, Chia-Hsuin Chang, MD, Chen-Ko Kuo, BS, Jen-Hau Chen, MD, Farzaneh Sorond, PhD

Findings show that high concentrations of CRP are associated with increased risk of stroke and cognitive impairment.

Meta Analysis

3 effects

8 years

Determinants	Outcome	Details
Inflammation Lymphatic system	Minor increase risk of Dementia Brain system	Moderate evidence 20.0%
Inflammation Lymphatic system	Minor increase risk of Cognitive deficit Brain system	Moderate evidence 20.0%
Inflammation Lymphatic system	Increased risk of Stroke Brain system	High evidence 70.0%