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Risk Factors
NutritionNutritionDrinks & beveragesBeveragesHerbHerbsSelfcareSelfcareContaminantContaminantsManufactured substancesManufactured
Outcomes
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A Periodic Diet that Mimics Fasting Promot...

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

07 Jul 2015Sebastian Brandhorst, In Young Choi, Min Wei, Chia Wei Cheng, Sargis Sedrakyan, Gerardo Navarrete, Louis Dubeau, Li Peng Yap, Ryan Park, Manlio Vinciguerra, Stefano Di Biase, Hamed Mirzaei, Mario G. Mirisola, Patra Childress, Lingyun Ji, Susan Groshen, Fabio Penna, Patrizio Odetti, Laura Perin, Peter S. Conti, Yuji Ikeno, Brian K. Kennedy, Pinchas Cohen, Todd E. Morgan, Tanya B. Dorff, Valter D. Longo

In a pilot clinical trial, three FMD cycles decreased risk factors/biomarkers for aging, diabetes, cardiovascular disease, and cancer without major adverse effects, providing support for the use of FMDs to promote healthspan.

Cohort Study
4 effects
75 days
38 subjects

Reported Outcomes

DeterminantsOutcomeDetails

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Obesity Musculoskeletal outcome
Minor decreased risk of Obesity
Musculoskeletal system

Moderate evidence
-3.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Blood Sugar - Hyperglycemia Lymphatic outcome
Minor decreased risk of Blood Sugar - Hypergl...
Lymphatic system

Moderate evidence
-9.0%

Fasting Nutrition risk & protective factor
Minor Risk Factor Fasting
Nutrition

Fat Oxidation Musculoskeletal outcome
Minor decreased risk of Fat Oxidation
Musculoskeletal system

Moderate evidence
-4.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Oxidative stress Lymphatic outcome
Minor decreased risk of Oxidative stress
Lymphatic system

Moderate evidence
-20.0%

Risk Factors

NutritionBeveragesHerbsSelf-careContaminantsManufactured

Outcomes

Physical PerformanceBrain & Mental HealthCardiovascularDigestiveEndocrine & HormonesIntergumentary
Lymphatic & Immune systemMaternityRespiratoryReproductiveSensoryUrinary & Kidney

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