Hyperinsulinemia and risk of Alzheimer disease

12 Oct 2004Jose A. Luchsinger, MD, Ming-Xin Tang, PhD, Steven Shea, MD and Richard Mayeux, MD

Hyperinsulinemia is associated with a higher risk of AD and decline in memory.

Meta Analysis

3 effects

5 years

683 subjects

Determinants	Outcome	Details
Hyperinsulinemia Lymphatic system	Increased risk of Alzheimer's disease Brain system	High evidence 110.0%
Type 2 Diabetes Lymphatic system	Minor increase risk of Alzheimer's disease Brain system	Moderate evidence 39.0%
Hyperinsulinemia Lymphatic system	Minor decreased risk of Memory Brain system	Moderate evidence -35.0%