Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis

14 Aug 2012E. G. WilmotC. L. EdwardsonF. A. AchanaM. J. DaviesT. GorelyL. J. GrayK. KhuntiT. YatesEmail authorS. J. H. Biddle

Sedentary time is associated with an increased risk of diabetes, cardiovascular disease and cardiovascular and all-cause mortality; the strength of the association is most consistent for diabetes.

Meta Analysis
5 effects
794577 subjects

Reported Outcomes

CausesOutcomeCertainty

Sedentary Lifestyle Selfcare risk & protective factor

Atrial Fibrillation Cardiovascular outcome
Strong increased risk of Atrial Fibrillation
Cardiovascular system

High evidence
147.0%

Sedentary Lifestyle Selfcare risk & protective factor

Heart Attack (Myocardial infarction - ACS) Cardiovascular outcome
Strong increased risk of Heart Attack (Myocard...
Cardiovascular system

High evidence
147.0%

Sedentary Lifestyle Selfcare risk & protective factor

Type 2 Diabetes Lymphatic outcome
Strong increased risk of Type 2 Diabetes
Lymphatic system

High evidence
112.0%

Sedentary Lifestyle Selfcare risk & protective factor

Mortality Musculoskeletal outcome
Increased risk of Mortality
Musculoskeletal system

High evidence
49.0%

Sedentary Lifestyle Selfcare risk & protective factor

Cardiovascular Disease Cardiovascular outcome
Increased risk of Cardiovascular Disease
Cardiovascular system

High evidence
90.0%