Novel Antiplatelet Activity of Protocatechuic Acid through the Inhibition of High Shear Stress-Induced Platelet Aggregation

10 Dec 2012Keunyoung Kim, Ok-Nam Bae, Kyung-Min Lim, Ji-Yoon Noh, Seojin Kang, Ka Young Chung and Jin-Ho Chung

Results suggest that protocatechuic acid (PCA), a bioactive phytochemical from Lonicera (honeysuckle) flowers, may be a novel antiplatelet agent that can prevent thrombosis without increasing bleeding risks.

Animal Research
2 effects

Reported Outcomes

DeterminantsOutcomeDetails

Japanese honeysuckle (Lonicera japonica 忍冬藤 ) Herb risk & protective factor
Minor Protective Factor Japanese honeysuckle (...
Herb

Thrombosis Cardiovascular outcome
Minor decreased risk of Thrombosis
Cardiovascular system

Moderate evidence
-4.0%

Japanese honeysuckle (Lonicera japonica 忍冬藤 ) Herb risk & protective factor
Minor Protective Factor Japanese honeysuckle (...
Herb

Cardiovascular Disease Cardiovascular outcome
Minor decreased risk of Cardiovascular Disease
Cardiovascular system

Low evidence
-1.0%