Impact of intermittent fasting on health and disease processes

31 Oct 2016Mark P. Mattsona, Valter D. Longo, Michelle Harvie

Findings demonstrate efficacy for weight loss and improvements in multiple health indicators including insulin resistance and reductions in risk factors for cardiovascular disease.

Systematic review
11 effects

Reported Outcomes

DeterminantsOutcomeDetails

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Obesity Musculoskeletal outcome
Minor decreased risk of Obesity
Musculoskeletal system

High evidence
-3.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Type 2 Diabetes Lymphatic outcome
Minor decreased risk of Type 2 Diabetes
Lymphatic system

Low evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Parkinson's Disease Brain outcome
Minor decreased risk of Parkinson's Disease
Brain system

Low evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Stroke Brain outcome
Minor decreased risk of Stroke
Brain system

Low evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Alzheimer's disease Brain outcome
Minor decreased risk of Alzheimer's disease
Brain system

Low evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Pancreatic cancer Digestive outcome
Minor decreased risk of Pancreatic cancer
Digestive system

Low evidence
-3.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Cardiovascular Disease Cardiovascular outcome
Minor decreased risk of Cardiovascular Disease
Cardiovascular system

Moderate evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Insulin Resistance Lymphatic outcome
Minor decreased risk of Insulin Resistance
Lymphatic system

Moderate evidence
-1.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Leukemia Lymphatic outcome
Minor decreased risk of Leukemia
Lymphatic system

Low evidence
-1.0%

Fasting Nutrition risk & protective factor
Strong Protective Factor Fasting
Nutrition

Insulin-like Human Growth Hormone (IGF-1) Endocrine outcome
Strong decrease risk of Insulin-like Human Gr...
Endocrine system

High evidence
-700.0%

Fasting Nutrition risk & protective factor
Minor Protective Factor Fasting
Nutrition

Oxidative stress Lymphatic outcome
Minor decreased risk of Oxidative stress
Lymphatic system

High evidence
-15.0%