Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study

21 Jan 2008C. S. Yajnik, S. S. Deshpande, A. A. Jackson, H. Refsum, S. Rao, D. J. Fisher, D. S. Bhat, S. S. Naik, K. J. Coyaji, C. V. Joglekar, N. Joshi, H. G. Lubree, V. U. Deshpande, S. S. Rege, and C. H. D. Fall

Low maternal vitamin B12 and high folate status may contribute to the epidemic of adiposity and type 2 diabetes in India.

Case-control study
4 effects
6 years
700 subjects

Reported Outcomes

DeterminantsOutcomeDetails

Folic Acid, Folate & Vitamin B9 Supplements Manufactured risk & protective factor
Minor Protective Factor Folic Acid, Folate & V...
Manufactured

Insulin Resistance Lymphatic outcome
Minor decreased risk of Insulin Resistance
Lymphatic system

Low evidence
-1.0%

Folic Acid, Folate & Vitamin B9 Supplements Manufactured risk & protective factor
Minor Risk Factor Folic Acid, Folate & V...
Manufactured

Parental Transmission of Type 2 Diabetes Maternity outcome
Minor increase risk of Parental Transmission...
Maternity system

Low evidence
11.0%

Foods rich in Vitamin B12 Nutrition risk & protective factor
Minor Risk Factor Foods rich in Vitamin B12
Nutrition

Parental Transmission of Type 2 Diabetes Maternity outcome
Minor increase risk of Parental Transmission...
Maternity system

Low evidence
11.0%

Foods rich in Alpha-Lipoic Acid (ALA) Nutrition risk & protective factor
Minor Protective Factor Foods rich in Alpha-Li...
Nutrition

Low birth weight Maternity outcome
Minor increase risk of Low birth weight
Maternity system

Low evidence
1.0%