Meta-Analysis: Obesity and the Risk for Gastroesophageal Reflux Disease and Its Complications

Howard Hampel, MD, PhD; Neena S. Abraham, MD, MSc(Epi); Hashem B. El-Serag, MD, MPH

Obesity is associated with a statistically significant increase in the risk for GERD symptoms, erosive esophagitis, and esophageal adenocarcinoma. The risk for these disorders seems to progressively increase with increasing weight.

Meta Analysis
1 effect

Reported Outcomes


Obesity Musculoskeletal outcome
Musculoskeletal system

Acid Reflux Digestive outcome
Increased risk of Acid Reflux
Digestive system

High evidence