Coffee (Caffeine) Health Risks

Caffeine is a stimulatory anti-sleep compound extracted from coffee beans. Habitual caffeine use leads to tolerance, which dulls several of caffeine’s effects.

Risk C Factor

Measured in mg

Western (Northern European) diet

Beverage

Decreased risk of Type 2 Diabetes Lymphatic system	2 studies Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia:... Study in 2009 -48% with Moderate evidence in 21 years 1,409 subjects Association of Coffee Drinking with Total and Cause-Specific Mortality Study in 2012 -40% with High evidence in 13 years 617,119 subjects
Decreased risk of Dementia Brain system	3 studies Midlife Coffee and Tea Drinking and the Risk of Late-Life Dementia:... Study in 2009 -66% with Moderate evidence in 21 years 1,409 subjects Association of Coffee Consumption with Total and Cause-Specific Mor... Study in 2015 -31% with Moderate evidence in 22 years 208,501 subjects Relationships Between Caffeine Intake and Risk for Probable Dementi... Study in 2016 -26% with High evidence in 10 years 6,467 subjects
Minor decreased risk of Cardiovascular Disease Cardiovascular system	2 studies Association of Coffee Drinking with Total and Cause-Specific Mortality Study in 2012 -28% with High evidence in 13 years 617,119 subjects Association of Coffee Consumption with Total and Cause-Specific Mor... Study in 2015 -12% with Moderate evidence in 22 years 208,501 subjects
Minor decreased risk of Cognitive deficit Brain system	1 study Relationships Between Caffeine Intake and Risk for Probable Dementi... Study in 2016 -26% with High evidence in 10 years 6,467 subjects
Minor decreased risk of Depression Brain system	1 study Coffee, tea, caffeine and risk of depression: A systematic review a... -24% with High evidence in 24 yrs 346,913 subjects
Minor decreased risk of Skin cancer Intergumentary system	1 study Coffee May Be Associated With a Lower Risk of Malignant Melanoma Study in 2015 -20% with High evidence in 10 years 447,357 subjects
Minor decreased risk of Stroke Brain system	2 studies Association of Coffee Consumption with Total and Cause-Specific Mor... Study in 2015 -19% with Moderate evidence in 22 years 208,501 subjects Association of Coffee Drinking with Total and Cause-Specific Mortality Study in 2012 -16% with High evidence in 13 years 617,119 subjects

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Minor increase risk of Cortisol Endocrine system	1 study Dose effect of caffeine on testosterone and cortisol responses to r... Study in 2008 +52% with Moderate evidence in 2 hours 21 subjects
Minor increase risk of Lung cancer Respiratory system	1 study Association of Coffee Consumption with Total and Cause-Specific Mor... Study in 2015 +39% with Moderate evidence in 22 years 208,501 subjects
Minor increase risk of Pancreatic cancer Digestive system	1 study Association of Coffee Consumption with Total and Cause-Specific Mor... Study in 2015 +8% with Moderate evidence in 22 years 208,501 subjects
Minor increase risk of Inflammation Lymphatic system	4 studies Effects of caffeinated and decaffeinated coffee on biological risk ... Study in 2012 +95% with Low evidence in 8 weeks 45 subjects Association of coffee consumption with serum adiponectin, leptin, i... Study in 2012 -20% with Moderate evidence 3,317 subjects Coffee and tea consumption in relation to inflammation and basal gl... Study in 2011 +11% with Low evidence in 4 years 10,747 subjects Coffee consumption and markers of inflammation and endothelial dysf... Study in 2006 -3% with Moderate evidence in 4 years 1,393 subjects
Minor increase risk of Heart Rate Cardiovascular system	1 study Dose response effects of a caffeine-containing energy drink on musc... Study in 2012 +3% with Low evidence in 1 hr 12 subjects
Strong decrease risk of Pregnancy & Birth Maternity system	1 study Lifestyle factors and reproductive health: taking control of your f... Study in 2013 -400% with High evidence in 7 days

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Cancer protection

The World Health Organization cites that there is an overwhelming amount of research that coffee can promote health and actually inhibit cancer. However, they did note that drinking coffee at temperatures in excess of 140 degrees Fahrenheit can increase the risk of cancers of the throat and esophagus. This temperature is much higher than which coffee is typically consumed.

Caffeine is highly stimulatory and a systemic vasoconstrictor. Caution should be exerted if one is either not used to caffeine ingestion or currently has high blood pressure. Caffeine should not be used as a supplement in those with cardiac impairments without prior consultation of one's doctor. Caffeine can also have an effect on ones quality of sleep; while you may be able to fall asleep, it will be of inferior quality. Chronic ingestion of caffeine reduce performance benefits of caffeine.Researchers tend to use a dosage range of 4-6mg/kg bodyweight.