Associations of job strain and lifestyle risk factors with risk of coronary artery disease: a met...

13 May 2013Mika Kivimäki, PhD, Solja T. Nyberg, MSc, Eleonor I. Fransson, PhD, Katriina Heikkilä, PhD, Lars Alfredsson, PhD, Annalisa Casini, PhD, Els Clays, PhD, Dirk De Bacquer, PhD, Nico Dragano, PhD, Jane E. Ferrie, PhD, Marcel Goldberg, MD, Mark Hamer, PhD, Markus Jokela, PhD, Robert Karasek, PhD, France Kittel, PhD, Anders Knutsson, MD, Markku Koskenvuo, MD, Maria Nordin, PhD, Tuula Oksanen, PhD, Jaana Pentti, BSc, Reiner Rugulies, PhD, Paula Salo, PhD, Johannes Siegrist, PhD, Sakari B. Suominen, MD, Töres Theorell, MD, Jussi Vahtera, MD, Marianna Virtanen, PhD, Peter J.M. Westerholm, MD, Hugo Westerlund, PhD, Marie Zins, MD, Andrew Steptoe, DSc, Archana Singh-Manoux, PhD, G. David Batty, PhD for the IPD-Work Consortium

The risk of coronary artery disease was highest among participants who reported job strain and an unhealthy lifestyle; those with job strain and a healthy lifestyle had half the rate of disease. A healthy lifestyle may substantially reduce disease risk among people with job strain.

Meta Analysis
5 effects
7 years
102 subjects

Reported Outcomes

VariablesOutcomeEffectLatency

Job Stress Brain outcome

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Coronary Heart ...
Cardiovascular

Strong Increase

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Smoking Contaminant risk & protective factor
Smoking
Contaminant

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Coronary Heart ...
Cardiovascular

Strong Increase

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Alcohol Beverage risk & protective factor
Alcohol
Beverage

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Coronary Heart ...
Cardiovascular

Strong Increase

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Sedentary Lifestyle Selfcare risk & protective factor

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Coronary Heart ...
Cardiovascular

Strong Increase

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Obesity Musculoskeletal outcome
Obesity
Musculoskeletal

Coronary Heart Disease (Ischaemic Heart Disease) Cardiovascular outcome
Coronary Heart ...
Cardiovascular

Strong Increase

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