Antidepressant use and risk of hip fractures among community-dwelling persons with and without Alzheimer's disease

05 Jan 2017Sanna Torvinen-Kiiskinen, Anna-Maija Tolppanen, Marjaana Koponen, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen, Heidi Taipale

Antidepressant use nearly doubles the risk of hip fracture among community-dwelling persons with Alzheimer's disease

Cross-section study
3 effects
151473 subjects

Reported Outcomes

CausesOutcomeCertainty

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Fracture Musculoskeletal outcome
Strong increased risk of Fracture
Musculoskeletal system

Evidence: Low
128.0%

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Fracture Musculoskeletal outcome
Strong increased risk of Fracture
Musculoskeletal system

Evidence: Moderate
201.0%

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Hip fracture Musculoskeletal outcome
Strong increased risk of Hip fracture
Musculoskeletal system

Evidence: Very High
128.0%