Cumulative Use of Strong Anticholinergics and Incident Dementia A Prospective Cohort Study

01 Feb 2015Shelly L. Gray, PharmD, MS; Melissa L. Anderson, MS; Sascha Dublin, MD, PhD; et al

Higher cumulative anticholinergic use is associated with an increased risk for dementia

Cohort Study
2 effects
12 years
3434 subjects

Reported Outcomes

VariablesOutcomeEffectLatency

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Dementia Brain outcome

Strong Increase

Login required to view

Antidepressants Manufactured risk & protective factor
Antidepressants
Manufactured

Alzheimer's disease Brain outcome

Strong Increase

Login required to view