A Comparison of Treating Metabolic Acidosis in CKD Stage 4 Hypertensive Kidney Disease with Fruit...

07 Mar 2013Nimrit Goraya, Jan Simoni, Chan-Hee Jo, Donald E. Wesson

One year of fruits and vegetables or NaHCO3 in individuals with stage 4 CKD yielded eGFR that was not different, was associated with higher-than-baseline PTCO2, and was associated with lower-than-baseline urine indices of kidney injury. The data indicate that fruits and vegetables improve metabolic acidosis and reduce kidney injury in stage 4 CKD without producing hyperkalemia.

Cohort Study
6 effects
1 year
141 subjects

Reported Outcomes

VariablesOutcomeEffectLatency

Fruits Nutrition risk & protective factor
Fruits
Nutrition

Chronic kidney disease  Urinary outcome

Strong Decrease

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Vegetables Nutrition risk & protective factor
Vegetables
Nutrition

Chronic kidney disease  Urinary outcome

Strong Decrease

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Sodium Bicarbonate Manufactured risk & protective factor
Sodium Bicarb...
Manufactured

Chronic kidney disease  Urinary outcome

Strong Decrease

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Sodium Bicarbonate Manufactured risk & protective factor
Sodium Bicarb...
Manufactured

Kidney Damage (Proteinuria) Urinary outcome

Strong Decrease

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Fruits Nutrition risk & protective factor
Fruits
Nutrition

Kidney Damage (Proteinuria) Urinary outcome

Strong Decrease

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Vegetables Nutrition risk & protective factor
Vegetables
Nutrition

Kidney Damage (Proteinuria) Urinary outcome

Strong Decrease

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