Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Syste...

18 Nov 2013Jennifer M. Gierisch, Remy R. Coeytaux, Rachel Peragallo Urrutia, Laura J. Havrilesky, Patricia G. Moorman, William J. Lowery, Michaela Dinan, Amanda J. McBroom, Vic Hasselblad, Gillian D. Sanders and Evan R. Myers

ompared with never use, ever use of oral contraceptives is significantly associated with decreases in colorectal and endometrial cancers and increases in breast cancers. Although elevated breast cancer risk was small, relatively high incidence of breast cancers means that oral contraceptives may contribute to a substantial number of cases.

Systematic review
4 effects
10 years

Reported Outcomes

VariablesOutcomeEffectLatency

Contraceptive pills Manufactured risk & protective factor
Contraceptive...
Manufactured

Colorectal Cancer Digestive outcome

Strong Decrease

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Contraceptive pills Manufactured risk & protective factor
Contraceptive...
Manufactured

Breast Cancer Reproductive outcome
Breast Cancer
Reproductive

Notable Increase

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Contraceptive pills Manufactured risk & protective factor
Contraceptive...
Manufactured

Uterine Cancer Reproductive outcome
Uterine Cancer
Reproductive

Strong Decrease

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Contraceptive pills Manufactured risk & protective factor
Contraceptive...
Manufactured

Central Nervous System Cancer Brain outcome

Notable Increase

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