Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Men...

09 Nov 2016S. H. Gag, H. J. Jones, S. Burgess, J. Bowden, G. Davey Smith, S. Zammit and M. R. Munafò

Our results provide some that cannabis initiation increases the risk of schizophrenia, although the size of the causal estimate is small. We find stronger evidence that schizophrenia risk predicts cannabis initiation, possibly as genetic instruments for schizophrenia are stronger than for cannabis initiation.

Case-control study
1 effect
150064 subjects

Reported Outcomes


Marijuana Herb risk & protective factor

Schizophrenia Brain outcome

Notable Increase

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