Lymphatic outcome

Insulin Resistance

Insulin resistance (IR) is a pathological condition in which cells fail to respond normally to the hormone insulin. The body produces insulin when glucose starts to be released into the bloodstream from the digestion of carbohydrates in the diet. Normally this insulin response triggers glucose being taken into body cells, to be used for energy, and inhibits the body from using fat for energy. The level of glucose in the blood decreases as a result, staying within the normal range even when a large amount of carbohydrates is consumed. This reflects the healthy amount of insulin sensitivity. In contrast, when the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. This often remains undetected and can contribute to a diagnosis of type 2 diabetes or latent autoimmune diabetes of adults. Although this type of chronic insulin resistance is harmful, during acute illness it is actually a well-evolved protective mechanism. Recent investigations have revealed that insulin resistance helps to conserve the brain's glucose supply by preventing muscles from taking up excessive glucose. Insulin resistance should even be strengthened under harsh metabolic conditions such as pregnancy, during which the expanding fetal brain demands more glucose.

People who develop type 2 diabetes usually pass through earlier stages of insulin resistance and prediabetes, although those often go undiagnosed. Insulin resistance syndrome is a syndrome (a set of signs and symptoms) resulting from insulin resistance; it is also called metabolic syndrome.

Lymphatic
26 causes

Related to Insulin Resistance

Causes of Insulin Resistance : Reducing Your Risk

FactorsEffectEvidenceStudies

Coffee (Caffeine) Beverage risk & protective factor

Minor Decrease

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Red Wine Beverage risk & protective factor
Red Wine
Beverage

Strong Decrease

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Diet Soda Beverage risk & protective factor
Diet Soda
Beverage

Notable Increase

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Unsaturated fat Nutrition risk & protective factor

Notable Decrease

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Green Tea Beverage risk & protective factor
Green Tea
Beverage

Strong Decrease

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Yoga Selfcare risk & protective factor
Yoga
Selfcare

Minor Decrease

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Cinnamon Herb risk & protective factor

Minor Decrease

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High Intensity Interval Training (HIIT) Selfcare risk & protective factor

Minor Decrease

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Ketogenic diet Nutrition risk & protective factor

Minor Increase

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 Sugar-Sweetened Beverages Beverage risk & protective factor

Strong Increase

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Refined grains Nutrition risk & protective factor

Minor Increase

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Folic Acid, Folate & Vitamin B9 Supplements Manufactured risk & protective factor
Folic Acid, F...
Manufactured

Minor Decrease

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Fasting Nutrition risk & protective factor
Fasting
Nutrition

Minor Decrease

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Soy Nutrition risk & protective factor
Soy
Nutrition

Notable Decrease

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Bitter Melon (Momordica charantia) Nutrition risk & protective factor

Notable Decrease

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Blood Donation Selfcare risk & protective factor

Strong Decrease

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Cortisol Endocrine outcome
Cortisol
Endocrine

Strong Increase

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Sleep Musculoskeletal outcome
Sleep
Musculoskeletal

Strong Decrease

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Poor sleep Musculoskeletal outcome
Poor sleep
Musculoskeletal

Strong Increase

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Cacao Nutrition risk & protective factor
Cacao
Nutrition

Strong Decrease

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Running Selfcare risk & protective factor
Running
Selfcare

Strong Decrease

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Strength Training Selfcare risk & protective factor

Notable Decrease

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Schizophrenia Brain outcome

Strong Increase

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Early Menarche Reproductive outcome
Early Menarche
Reproductive

Notable Increase

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Obesity Musculoskeletal outcome
Obesity
Musculoskeletal

Strong Increase

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Saturated Fat Nutrition risk & protective factor
Saturated Fat
Nutrition

Strong Increase

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PM25 Outdoor Air Pollution Contaminant risk & protective factor
PM25 Outdoor ...
Contaminant

Strong Increase

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Insulin Resistance outcomes

OutcomesEffectEvidenceReferences

Acne Vulgaris Intergumentary outcome
Acne Vulgaris
Intergumentary

Strong Increase

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