Lymphatic outcome

Insulin Resistance

Insulin resistance (IR) is a pathological condition in which cells fail to respond normally to the hormone insulin. The body produces insulin when glucose starts to be released into the bloodstream from the digestion of carbohydrates in the diet. Normally this insulin response triggers glucose being taken into body cells, to be used for energy, and inhibits the body from using fat for energy. The level of glucose in the blood decreases as a result, staying within the normal range even when a large amount of carbohydrates is consumed. This reflects the healthy amount of insulin sensitivity. In contrast, when the body produces insulin under conditions of insulin resistance, the cells are resistant to the insulin and are unable to use it as effectively, leading to high blood sugar. Beta cells in the pancreas subsequently increase their production of insulin, further contributing to a high blood insulin level. This often remains undetected and can contribute to a diagnosis of type 2 diabetes or latent autoimmune diabetes of adults. Although this type of chronic insulin resistance is harmful, during acute illness it is actually a well-evolved protective mechanism. Recent investigations have revealed that insulin resistance helps to conserve the brain's glucose supply by preventing muscles from taking up excessive glucose. Insulin resistance should even be strengthened under harsh metabolic conditions such as pregnancy, during which the expanding fetal brain demands more glucose.

People who develop type 2 diabetes usually pass through earlier stages of insulin resistance and prediabetes, although those often go undiagnosed. Insulin resistance syndrome is a syndrome (a set of signs and symptoms) resulting from insulin resistance; it is also called metabolic syndrome.

Lymphatic
26 causes

There are 16 factors preventing the outcome of Insulin Resistance, including:

Protective FactorsStudies

Cacao Nutrition risk & protective factor
Cacao
Nutrition

2 studies

Sleep

1 study

Red Wine Beverage risk & protective factor
Red Wine
Beverage

1 study

Blood Donation Selfcare risk & protective factor

2 studies

Running Selfcare risk & protective factor
Running
Selfcare

1 study

Green Tea Beverage risk & protective factor
Green Tea
Beverage

1 study

Unsaturated fat Nutrition risk & protective factor

1 study

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There are 11 factors increasing the risk of Insulin Resistance, including:

Risk FactorsStudies
Obesity

 Sugar-Sweetened Beverages Beverage risk & protective factor

1 study

Poor sleep

2 studies

Schizophrenia

1 study

PM25 Outdoor Air Pollution Contaminant risk & protective factor

1 study

Cortisol

1 study

Saturated Fat Nutrition risk & protective factor
Saturated Fat
Nutrition

1 study

Possible outcomes of Insulin Resistance

OutcomesReferences
Acne Vulgaris

Related to Insulin Resistance

Add Insulin Resistance